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Article

Functional specialization of chordate CDK1 paralogs during oogenic meiosis.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Øvrebø Jan Inge, Campsteijn Coen, Kourtesis Ioannis, Hausen Harald, Raasholm Martina, Thompson Eric M

Abstract excerpt

Cyclin-dependent kinases (CDKs) are central regulators of eukaryotic cell cycle progression. In contrast to interphase CDKs, the mitotic phase CDK1 is the only CDK capable of driving the entire cell cycle and it can do so from yeast to mammals. Interestingly, plants and the marine chordate, Oikopleura dioica, possess paralogs of the highly conserved CDK1 regulator. However, whereas in plants the 2 CDK1 paralogs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25714331
DOI: 10.1080/15384101.2015.1006000
PMCID: PMC4612768

Genes

CDK1

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