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Article

Co-expressed Cyclin D variants cooperate to regulate proliferation of germline nuclei in a syncytium.

Cell cycle (Georgetown, Tex.) - 1 Jan 2015

Subramaniam Gunasekaran, Campsteijn Coen, Thompson Eric M

Abstract excerpt

The role of the G1-phase Cyclin D-CDK 4/6 regulatory module in linking germline stem cell (GSC) proliferation to nutrition is evolutionarily variable. In invertebrate Drosophila and C. elegans GSC models, G1 is nearly absent and Cyclin E is expressed throughout the cell cycle, whereas vertebrate spermatogonial stem cells have a distinct G1 and Cyclin D1 plays an important role in GSC renewal. In the invertebrate,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25928155
DOI: 10.1080/15384101.2015.1041690
PMCID: PMC4612681

Genes

GSC
CDK6

Provenance

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Co-expressed Cyclin D variants cooperate to regulate proliferation of germline nuclei in a syncytium.PMID 25928155Read ↗

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