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Article

ATP exhibits antimicrobial action by inhibiting bacterial utilization of ferric ions.

Scientific reports - 25 Feb 2015

Tatano Yutaka, Kanehiro Yuichi, Sano Chiaki, Shimizu Toshiaki, Tomioka Haruaki

Abstract excerpt

ATP up-regulates macrophage antimycobacterial activity in a P2X7-dependent manner, but little is known about whether ATP directly exhibits antimicrobial effects against intracellular mycobacteria. In this study, we found that ATP inhibited the growth of various bacteria, including Staphylococcus, Pseudomonas, and mycobacteria, without damaging bacterial surface structures. Using gene technology, we newly...

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Identifiers

PMID: 25712807
DOI: 10.1038/srep08610
PMCID: PMC4339799

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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