Article
Cytadherence of Mycoplasma pneumoniae induces inflammatory responses through autophagy and toll-like receptor 4.
Infection and immunity - 1 Jul 2014
Shimizu Takashi, Kimura Yui, Kida Yutaka, Kuwano Koichi, Tachibana Masato, Hashino Masanori, Watarai Masahisa
Abstract excerpt
Mycoplasma pneumoniae causes pneumonia, tracheobronchitis, pharyngitis, and asthma in humans. The pathogenesis of M. pneumoniae infection is attributed to excessive immune responses. We previously demonstrated that M. pneumoniae lipoproteins induced inflammatory responses through Toll-like receptor 2 (TLR2). In the present study, we demonstrated that M. pneumoniae induced strong inflammatory responses in...
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