Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis.

European journal of biochemistry - 1 Feb 2003

Chopra Puneet, Singh Anubha, Koul Anil, Ramachandran S, Drlica Karl, Tyagi Anil K, Singh Yogendra

Abstract excerpt

Pathogenicity of Mycobacterium tuberculosis is closely related to its ability to survive and replicate in the hostile environment of macrophages. For some pathogenic bacteria, secretion of ATP-utilizing enzymes into the extracellular environment aids in pathogen survival via P2Z receptor-mediated, ATP-induced death of infected macrophages. A component of these enzymes is nucleoside diphosphate kinase (Ndk). The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenine
Share to Adenosine Triphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Death

Share to Glutamine

Share to GTP Phosphohydrolases

Share to Histidine

Share to Nucleoside-Diphosphate Kinase

Share to Receptors, Purinergic P2X7

Source

Identifiers

PMID: 12581202
DOI: 10.1046/j.1432-1033.2003.03402.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis.PMID 12581202Read ↗

The TIR-domain containing effectors BtpA and BtpB from <i>Brucella abortus</i> block energy metabolismSemantic proximity Read ↗

An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.Semantic proximity Read ↗

Protein Kinase G from Pathogenic Mycobacteria Promotes Survival Within MacrophagesSemantic proximity Read ↗

Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis.Semantic proximity Read ↗

Identification and Characterization of a Unique Adenosine Kinase from <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages.Semantic proximity Read ↗

Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis.Semantic proximity Read ↗

Bacterial Eukaryotic Type Serine-Threonine Protein Kinases: From Structural Biology to Targeted Anti-Infective Drug DesignSemantic proximity Read ↗

Mycobacterium tuberculosis protein kinase K confers survival advantage during early infection in mice and regulates growth in culture and during persistent infection: implications for immune modulationSemantic proximity Read ↗

Enzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.Semantic proximity Read ↗

Revisiting trypanosomatid nucleoside diphosphate kinasesSemantic proximity Read ↗

Protein kinase A (PknA) of Mycobacterium tuberculosis is independently activated and is critical for growth in vitro and survival of the pathogen in the host.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.