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Article

Siderocalin inhibits the intracellular replication of Mycobacterium tuberculosis in macrophages.

FEMS immunology and medical microbiology - 1 Feb 2010

Johnson Erin E, Srikanth Chittur V, Sandgren Andreas, Harrington Lynne, Trebicka Estela, Wang Lijian, Borregaard Niels, Murray Megan, Cherayil Bobby J

Abstract excerpt

Siderocalin is a secreted protein that binds to siderophores to prevent bacterial iron acquisition. While it has been shown to inhibit the growth of Mycobacterium tuberculosis (M.tb) in extracellular cultures, its effect on this pathogen within macrophages is not clear. Here, we show that sideroc...

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Identifiers

PMID: 19863663
DOI: 10.1111/j.1574-695X.2009.00622.x
PMCID: PMC2822896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19863663-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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