Article
Genetic polymorphism of ABCB1 gene (C3435T) in patients with inflammatory bowel diseases. Is there any gender dependency?
Pharmacological reports : PR - 1 Apr 2015
Jaźwińska-Tarnawska Ewa, Jęśkowiak Izabela, Waszczuk Ewa, Mulak Agata, Głowacka Krystyna, Hurkacz Magdalena, Paradowski Leszek, Zaleska Zofia, Wiela-Hojeńska Anna
Abstract excerpt
BACKGROUND: In recent years, an increasing incidence of inflammatory bowel disease (IBD) has been reported, mainly as Crohn's disease (CD) and ulcerative colitis (UC). The individual susceptibility, the disease's course and response to the applied therapy is likely due to genetic factors such as ABCB1 gene mutations, exemplified by C3435T polymorphism. The aim of the study was to evaluate the distribution of...
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