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Article

The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons.

Molecular biology of the cell - 1 Jul 2006

Huang Jinhong, Sakai Ryuichi, Furuichi Teiichi

Abstract excerpt

Crk-associated substrate (Cas) is a tyrosine-phosphorylated docking protein that is indispensable for the regulation of the actin cytoskeletal organization and cell migration in fibroblasts. The function of Cas in neurons, however, is poorly understood. Here we report that Cas is dominantly enriched in the brain, especially the cerebellum, of postnatal mice. During cerebellar development, Cas is highly tyrosine...

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Identifiers

PMID: 16687575
DOI: 10.1091/mbc.e05-12-1122
PMCID: PMC1483050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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