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Article

Combined signaling through ERK, PI3K/AKT, and RAC1/p38 is required for met-triggered cortical neuron migration.

The Journal of biological chemistry - 24 Feb 2006

Segarra Joseph, Balenci Laurent, Drenth Thijs, Maina Flavio, Lamballe Fabienne

Abstract excerpt

Cell migration is a complex biological process playing a key role in physiological and pathological conditions. During central nervous system development, positioning and function of cortical neurons is tightly regulated by cell migration. Recently, signaling events involving the urokinase-type plasminogen activator receptor, which is a key regulator for the activation of hepatocyte growth factor (HGF), have been...

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Share to Extracellular Signal-Regulated MAP Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to JNK Mitogen-Activated Protein Kinases

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Share to Proto-Oncogene Proteins c-met

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Source

Identifiers

PMID: 16361255
DOI: 10.1074/jbc.M508298200

Genes

HGF
RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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