Article
Mass cytometry analysis shows that a novel memory phenotype B cell is expanded in multiple myeloma.
Cancer immunology research - 1 Jun 2015
Hansmann Leo, Blum Lisa, Ju Chia-Hsin, Liedtke Michaela, Robinson William H, Davis Mark M
Abstract excerpt
It would be very beneficial if the status of cancers could be determined from a blood specimen. However, peripheral blood leukocytes are very heterogeneous between individuals, and thus high-resolution technologies are likely required. We used cytometry by time-of-flight and next-generation sequencing to ask whether a plasma cell cancer (multiple myeloma) and related precancerous states had any consistent effect...
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