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Article

Pathogenesis beyond the cancer clone(s) in multiple myeloma

3 Apr 2015

Abstract excerpt

Over the past 4 decades, basic research has provided crucial information regarding the cellular and molecular biology of cancer. In particular, the relevance of cancer microenvironment (including both cellular and noncellular elements) and the concept of clonal evolution and heterogeneity have emerged as important in cancer pathogenesis, immunologic escape, and resistance to therapy. Multiple myeloma (MM), a...

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PMID: 25838343
DOI: 10.1182/blood-2014-11-568881

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