Article
Defining the Mer1 and Nam8 meiotic splicing regulons by cDNA rescue.
RNA (New York, N.Y.) - 1 Sept 2011
Qiu Zhicheng R, Schwer Beate, Shuman Stewart
Abstract excerpt
Meiosis-specific pre-mRNA splicing in budding yeast embraces multiple pre-mRNA targets grouped into regulons defined by their genetic requirements for vegetatively optional splicing factors (e.g., splicing enhancer Mer1 and the U1 snRNP subunit Nam8) or snRNA modifications (trimethylguanosine caps). Here, we genetically demarcate a complete meiotic splicing regulon by the criterion of cDNA bypass of the...
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