Article
Meiotic Interactors of a Mitotic Gene TAO3 Revealed by Functional Analysis of its Rare Variant.
G3 (Bethesda, Md.) - 9 Aug 2016
Gupta Saumya, Radhakrishnan Aparna, Nitin Rachana, Raharja-Liu Pandu, Lin Gen, Steinmetz Lars M, Gagneur Julien, Sinha Himanshu
Abstract excerpt
Studying the molecular consequences of rare genetic variants has the potential to identify novel and hitherto uncharacterized pathways causally contributing to phenotypic variation. Here, we characterize the functional consequences of a rare coding variant of TAO3, previously reported to contribute significantly to sporulation efficiency variation in Saccharomyces cerevisiae During mitosis, the common TAO3 allele...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.