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Article

Ceramide synthase 4 regulates stem cell homeostasis and hair follicle cycling.

The Journal of investigative dermatology - 1 Jun 2015

Peters Franziska, Vorhagen Susanne, Brodesser Susanne, Jakobshagen Kristin, Brüning Jens C, Niessen Carien M, Krönke Martin

Abstract excerpt

Ceramides are crucial for skin barrier function, but little is known about the regulation of epidermal appendages and whether stem cell populations that control their regeneration depend on specific ceramide species. Here we demonstrate that ceramide synthase 4 (CerS4) is highly expressed in the epidermis of adult mice where it is localized in the interfollicular epidermis and defined populations within the...

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Source

Identifiers

PMID: 25705848
DOI: 10.1038/jid.2015.60

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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