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Article

Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis.

Cell stem cell - 5 Dec 2013

Choi Yeon Sook, Zhang Yuhang, Xu Mingang, Yang Yongguang, Ito Mayumi, Peng Tien, Cui Zheng, Nagy Andras, Hadjantonakis Anna-Katerina, Lang Richard A, Cotsarelis George, Andl Thomas, Morrisey Edward E, Millar Sarah E

Abstract excerpt

Wnt/β-catenin signaling is a central regulator of adult stem cells. Variable sensitivity of Wnt reporter transgenes, β-catenin's dual roles in adhesion and signaling, and hair follicle degradation and inflammation resulting from broad deletion of epithelial β-catenin have precluded clear understanding of Wnt/β-catenin's functions in adult skin stem cells. By inducibly deleting β-catenin globally in skin...

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Identifiers

PMID: 24315444
DOI: 10.1016/j.stem.2013.10.003
PMCID: PMC3900235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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