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Article

Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases.

Annual review of genetics - 1 Jan 2011

Suzuki Tsutomu, Nagao Asuteka, Suzuki Takeo

Abstract excerpt

Mitochondria are eukaryotic organelles that generate most of the energy in the cell by oxidative phosphorylation (OXPHOS). Each mitochondrion contains multiple copies of a closed circular double-stranded DNA genome (mtDNA). Human (mammalian) mtDNA encodes 13 essential subunits of the inner membrane complex responsible for OXPHOS. These mRNAs are translated by the mitochondrial protein synthesis machinery, which...

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PMID: 21910628
DOI: 10.1146/annurev-genet-110410-132531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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