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Mitochondrial tRNA mutations in 887 Chinese subjects with hearing loss.

Mitochondrion - 1 May 2020

Zheng Jing, Bai Xiaohui, Xiao Yun, Ji Yanchun, Meng Feilong, Aishanjiang Maerhaba, Gao Yinglong, Wang Haibo, Fu Yong, Guan Min-Xin

Abstract excerpt

Mutations in the mitochondrial tRNAs have been reported to be the important cause of hearing loss. However, only a few cases have been identified thus far and the prevalence of mitochondrial tRNA mutations in hearing-impaired patients remain unclear. Here we performed the mutational analysis of 22 mitochondrial tRNA genes in a large cohort of 887 Han Chinese subjects with hearing loss by Sanger sequencing. The...

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Source

Identifiers

PMID: 32169613
DOI: 10.1016/j.mito.2020.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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