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Transfer RNA Mutation Associated with Type 2 Diabetes Mellitus

16 Jun 2023

Abstract excerpt

Transfer RNA (tRNA) genes in the mitochondrial DNA genome play an important role in protein synthesis. The 22 tRNA genes carry the amino acid that corresponds to that codon but changes in the genetic code often occur such as gene mutations that impact the formation of adenosine triphosphate (ATP). Insulin secretion does not occur because the mitochondria cannot work optimally. tRNA mutation may also be caused by...

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PMID: 37372155
DOI: 10.3390/biology12060871

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