Article
Mutational Screening for Mitochondrial tRNA Genes in 100 Women with Pre-Eclampsia.
Human heredity - 1 Jan 2022
Zhou Baohua, Chu Xuelian, Zhang Caijuan, Liang Xiufeng
Abstract excerpt
INTRODUCTION: Impairment of mitochondrial function caused by pathogenic mitochondrial DNA (mtDNA) mutations has been found to be associated with pre-eclampsia (PE). However, the underlying mechanism of PE remains poorly undetermined. The aim of this study is to evaluate the relationship between mitochondrial tRNA (mt-tRNA) variants and PE. METHODS: The mt-tRNA variants in a cohort of 100 pregnant women with PE...
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