Article
CD83 and GRASP55 interact in human dendritic cells.
Biochemical and biophysical research communications - 27 Mar 2015
Stein Marcello F, Blume Katja, Heilingloh Christiane S, Kummer Mirko, Biesinger Brigitte, Sticht Heinrich, Steinkasserer Alexander
Abstract excerpt
CD83 is one of the best known surface markers for mature human dendritic cells (DCs). The full-length 45 kDa type-I membrane-bound form (mbCD83) is strongly glycosylated upon DCs maturation. As co-stimulatory properties of CD83 are attributed to mbCD83 surface expression is required for efficient T-cell stimulation by mature DCs. By yeast two-hybrid screening, we were able to identify GRASP55 as interaction...
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