Article
CD83 acts as immediate early response gene in activated macrophages and exhibits specific intracellular trafficking properties.
Biochemical and biophysical research communications - 5 Mar 2023
Langguth Pia, Peckert-Maier Katrin, Beck Philipp, Kuhnt Christine, Draßner Christina, Deinzer Andrea, Steinkasserer Alexander, Wild Andreas B
Abstract excerpt
Macrophages (MΦ) are remarkably plastic cells, which assume phenotypes in every shade between a pro-inflammatory classical activation, and anti-inflammatory or resolving activation. Therefore, elucidation of mechanisms involved in shaping MΦ plasticity and function is key to understand their role during immunological balance. The immune-modulating CD83 molecule is expressed on activated immune cells and various...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
