Article
Suppressor of cytokine signaling 1 gene expression and polymorphisms in systemic lupus erythematosus.
Lupus - 1 May 2010
Chan H C, Ke L Y, Chang L L, Liu C C, Hung Y H, Lin C H, Li R N, Tsai W C, Liu H W, Yen J H
Abstract excerpt
With the aim of investigating the role of suppressor of cytokine signaling 1 (SOCS1) in the pathogenesis of systemic lupus erythematosus, 107 patients with systemic lupus erythematosus, 101 healthy controls, and 151 patients with ankylosing spondylitis were enrolled in this study. SOCS1 mRNA level was measured by the method of quantitative real-time polymerase chain reaction. SOCS1 polymorphisms were detected by...
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