Article
Less is more: an adaptive branch-site random effects model for efficient detection of episodic diversifying selection.
Molecular biology and evolution - 1 May 2015
Smith Martin D, Wertheim Joel O, Weaver Steven, Murrell Ben, Scheffler Konrad, Kosakovsky Pond Sergei L
Abstract excerpt
Over the past two decades, comparative sequence analysis using codon-substitution models has been honed into a powerful and popular approach for detecting signatures of natural selection from molecular data. A substantial body of work has focused on developing a class of "branch-site" models whic...
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