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A Codon Model for Associating Phenotypic Traits with Altered Selective Patterns of Sequence Evolution.

Systematic biology - 15 Apr 2021

Halabi Keren, Karin Eli Levy, Guéguen Laurent, Mayrose Itay

Abstract excerpt

Detecting the signature of selection in coding sequences and associating it with shifts in phenotypic states can unveil genes underlying complex traits. Of the various signatures of selection exhibited at the molecular level, changes in the pattern of selection at protein-coding genes have been of main interest. To this end, phylogenetic branch-site codon models are routinely applied to detect changes in...

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Identifiers

PMID: 33252676
DOI: 10.1093/sysbio/syaa087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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