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BABAPPAΩ: Diagnosing the Identifiability of Episodic Selection under Branch–Site Evolution Using Likelihood-Free Neural Inference

2026-02-24

Abstract excerpt

Episodic positive selection acting on specific evolutionary lineages is a longstanding yet intrinsically difficult target of molecular inference. Classical branch–site methods formulate this problem as hypothesis testing under explicit codon substitution models, implicitly assuming that episodic selection is statistically identifiable from finite alignments. Under biologically realistic conditions—including recomb...

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Literature Corpus work: d05d09bf-c785-5a19-9dd0-06aebad98acc
DOI: 10.32942/x2r073

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