Article

A codon model for associating phenotypic traits with altered selective patterns of sequence evolution

2020-03-05

Abstract excerpt

Changes in complex phenotypes, such as pathogenicity levels, trophic lifestyle, and habitat shifts are brought on by multiple genomic changes: sub- and neofunctionalization, loss of function, and levels of gene expression. Thus, detecting the signature of selection in coding sequences and associating it with shifts in phenotypic state can unveil the genes underlying complex traits. Phylogenetic branch-site codon m...

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Literature Corpus work: 02f0eb98-2d4b-5a0e-a5d0-a034542acc55
DOI: 10.1101/2020.03.04.974584

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