Article
The evolving genomic landscape of myeloproliferative neoplasms.
Hematology. American Society of Hematology. Education Program - 5 Dec 2014
Nangalia Jyoti, Green Tony R
Abstract excerpt
Our understanding of the genetic basis of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) has moved forward at a staggering pace over the last decade. With the discoveries of underlying mutations in JAK2, MPL, and, most recently, calreticulin (CALR), that together account for ∼90% of patients with MPNs, these conditions are now among the best characterized of hematological malignancies....
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