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Article

bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability.

Nucleic acids research - 11 Mar 2015

Kiparaki Marianthi, Zarifi Ioanna, Delidakis Christos

Abstract excerpt

Proneural bHLH activators are expressed in all neuroectodermal regions prefiguring events of central and peripheral neurogenesis. Drosophila Sc is a prototypical proneural activator that heterodimerizes with the E-protein Daughterless (Da) and is antagonized by, among others, the E(spl) repressors. We determined parameters that regulate Sc stability in Drosophila S2 cells. We found that Sc is a very labile...

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Identifiers

PMID: 25694512
DOI: 10.1093/nar/gkv083
PMCID: PMC4357701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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