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Article

The relationship of TP53 and GRIN2B gene polymorphisms with risk of occurrence and progression of primary open-angle glaucoma in a Polish population.

Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Dec 2014

Nowak A, Przybylowska-Sygut K, Szymanek K, Szaflik J, Szaflik Jp, Majsterek I

Abstract excerpt

INTRODUCTION: Glaucoma is characterized by optic neuropathy of the retinal ganglion cells (RGCs). Retinal ganglian cell death may be mediated by apoptosis. TP53 is involved in this process. It can also be found that excitotoxicity contributes to apoptosis by excess stimulation of glutamate receptors. The aim of this study was to evaluate the relationship of the TP53 (rs1042522) and GRIN2B (rs3764028) gene...

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Source

Identifiers

PMID: 25693086
DOI: 10.5114/pjp.2014.48193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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