Article
Association between p53 codon 72 (Arg72Pro) polymorphism and primary open-angle glaucoma in Iranian patients.
Iranian biomedical journal - 1 Jan 2015
Neamatzadeh Hossein, Soleimanizad Reza, Atefi Aref, Zare-Shehneh Masoud, Gharibi Saba, Shekari Abolfazl, Rahimzadeh Amir Bahman
Abstract excerpt
BACKGROUND: Glaucomatous neuropathy is a type of cell death due to apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (POAG) has been studied in some ethnic groups. This study is the first association analysis of POAG and p53 codon 72 polymorphism in Iranian patients. METHODS: A cohort...
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