Article
TP53 codon 72 polymorphism and the risk of glaucoma in a north Indian cohort: A genetic association study.
Ophthalmic genetics - 1 Apr 2018
Gupta Shashank, Chatterjee Souradip, Chandra Abhishek, Maurya Om Prakash Singh, Mishra Ravindra Nath, Mukherjee Ashim, Mutsuddi Mousumi
Abstract excerpt
BACKGROUND: The TP53 codon 72 Proline-Arginine polymorphism (TP53 P72R) is the most widely studied candidate among those evaluated for a putative association between impaired apoptosis and glaucoma. Considering the earlier findings about enhanced apoptotic potential by the Arg variant of TP53 P72R and the conflicting results about its association with glaucoma, we initiated a hospital-based case-control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
