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Article

Analysis of the polymorphic variants of RAN and GEMIN3 genes and risk of Primary Open-Angle Glaucoma in the Polish population.

Ophthalmic genetics - 1 Apr 2018

Molasy Milena, Walczak Anna, Przybyłowska-Sygut Karolina, Zaleska-Żmijewska Anna, Szaflik Jerzy, Szaflik Jacek P, Majsterek Ireneusz

Abstract excerpt

BACKGROUND: Glaucoma is considered as a neurodegenerative disorder in which the optic nerve damage leads to irreversible blindness. Many scientific findings indicate miRNA implication in the neurodegeneration process. In this study, we aimed to evaluate the polymorphic variants of miRNA processing genes, RAN (rs14035) and GEMIN3 (rs197388), and their association with a risk of primary open-angle glaucoma (POAG)...

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Identifiers

PMID: 29095070
DOI: 10.1080/13816810.2017.1381978

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RAN

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