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Article

DXD motif-dependent and -independent effects of the chlamydia trachomatis cytotoxin CT166.

Toxins - 17 Feb 2015

Bothe Miriam, Dutow Pavel, Pich Andreas, Genth Harald, Klos Andreas

Abstract excerpt

The Gram-negative, intracellular bacterium Chlamydia trachomatis causes acute and chronic urogenital tract infection, potentially leading to infertility and ectopic pregnancy. The only partially characterized cytotoxin CT166 of serovar D exhibits a DXD motif, which is important for the enzymatic activity of many bacterial and mammalian type A glycosyltransferases, leading to the hypothesis that CT166 possess...

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Identifiers

PMID: 25690695
DOI: 10.3390/toxins7020621
PMCID: PMC4344646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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