Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion.

PLoS pathogens - 1 Sept 2020

Faris Robert, McCullough Alix, Andersen Shelby E, Moninger Thomas O, Weber Mary M

Abstract excerpt

As an obligate intracellular pathogen, host cell invasion is paramount to Chlamydia trachomatis proliferation. While the mechanistic underpinnings of this essential process remain ill-defined, it is predicted to involve delivery of prepackaged effector proteins into the host cell that trigger plasma membrane remodeling and cytoskeletal reorganization. The secreted effector proteins TmeA and TarP, have risen to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin-Related Protein 2-3 Complex
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Membrane

Share to Chlamydia trachomatis

Share to HeLa Cells

Share to Mutation

Share to Protein Domains

Share to Pseudopodia

Source

Open in PubMed Open full text

Identifiers

PMID: 32946535
DOI: 10.1371/journal.ppat.1008878
PMCID: PMC7526919

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Chlamydia trachomatis secreted effector TmeA hijacks the N-WASP-ARP2/3 actin remodeling axis to facilitate cellular invasion.PMID 32946535Read ↗

Pathogenic Puppetry: Manipulation of the Host Actin Cytoskeleton by Chlamydia trachomatisSemantic proximity Read ↗

A renewed tool kit to explore Chlamydia pathogenesis: from molecular genetics to new infection modelsSemantic proximity Read ↗

The <i>Chlamydia</i> protein CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35Semantic proximity Read ↗

Pathogenicity and virulence of Chlamydia trachomatis : Insights into host interactions, immune evasion, and intracellular survivalSemantic proximity Read ↗

Fluorescence-Reported Allelic Exchange Mutagenesis-Mediated Gene Deletion Indicates a Requirement for Chlamydia trachomatis Tarp during In Vivo Infectivity and Reveals a Specific Role for the C Terminus during Cellular Invasion.Semantic proximity Read ↗

The Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer ComponentsSemantic proximity Read ↗

The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces Chlamydia trachomatis Infectivity and GrowthSemantic proximity Read ↗

New Frontiers in Type III Secretion Biology: the Chlamydia PerspectiveSemantic proximity Read ↗

Uncivil Engineers: Chlamydia , Salmonella and Shigella Alter Cytoskeleton Architecture to Invade Epithelial CellsSemantic proximity Read ↗

The <i>Chlamydia</i> type III effector TarP alters the dynamics and organization of host cell focal adhesionsSemantic proximity Read ↗

Fluorescence-Reported Allelic Exchange Mutagenesis Reveals a Role for Chlamydia trachomatis TmeA in Invasion That Is Independent of Host AHNAKSemantic proximity Read ↗

Targeted Disruption of Chlamydia trachomatis Invasion by in Trans Expression of Dominant Negative Tarp Effectors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.