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Article

Reduced DNA methylation and hydroxymethylation in patients with systemic mastocytosis.

European journal of haematology - 1 Dec 2015

Leoni Cristina, Montagner Sara, Deho' Lorenzo, D'Antuono Rocco, De Matteis Giovanna, Marzano Angelo V, Merante Serena, Orlandi Ester M, Zanotti Roberta, Monticelli Silvia

Abstract excerpt

OBJECTIVE: As disruption of epigenetic control is a frequent event in solid tumors and leukemia, we investigated changes in DNA methylation (5mC) and hydroxymethylation (5hmC) in patients with systemic mastocytosis (SM), a rare myeloproliferative disease with a wide spectrum of severity, characte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25688802
DOI: 10.1111/ejh.12537

Genes

TET2
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25688802-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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