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Article

Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy.

International journal of molecular sciences - 2 Jun 2020

Martelli Margherita, Monaldi Cecilia, De Santis Sara, Bruno Samantha, Mancini Manuela, Cavo Michele, Soverini Simona

Abstract excerpt

In recent years, molecular characterization and management of patients with systemic mastocytosis (SM) have greatly benefited from the application of advanced technologies. Highly sensitive and accurate assays for KIT D816V mutation detection and quantification have allowed the switch to non-invasive peripheral blood testing for patient screening; allele burden has prognostic implications and may be used to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32498255
DOI: 10.3390/ijms21113987
PMCID: PMC7312790

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