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Article

Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis.

International journal of molecular sciences - 15 Mar 2021

Reszka Edyta, Jabłońska Ewa, Wieczorek Edyta, Valent Peter, Arock Michel, Nilsson Gunnar, Nedoszytko Bogusław, Niedoszytko Marek

Abstract excerpt

Systemic mastocytosis (SM) is a hematologic neoplasm with abnormal accumulation of mast cells in various organ systems such as the bone marrow, other visceral organs and skin. So far, only little is known about epigenetic changes contributing to the pathogenesis of SM. In the current article, we provide an overview of epigenetic changes that may occur and be relevant to mastocytosis, including mutations in genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33803981
DOI: 10.3390/ijms22062964
PMCID: PMC7999363

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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