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Article

Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder.

Oncotarget - 30 Jul 2015

Chatterjee Anindya, Ghosh Joydeep, Kapur Reuben

Abstract excerpt

Although more than 90% systemic mastocytosis (SM) patients express gain of function mutations in the KIT receptor, recent next generation sequencing has revealed the presence of several additional genetic and epigenetic mutations in a subset of these patients, which confer poor prognosis and inferior overall survival. A clear understanding of how genetic and epigenetic mutations cooperate in regulating the...

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Source

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Identifiers

PMID: 26158763
DOI: 10.18632/oncotarget.4213
PMCID: PMC4621888

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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