Article
Toll-Like Receptor Pathways in Autoimmune Diseases.
Clinical reviews in allergy & immunology - 1 Feb 2016
Chen Ji-Qing, Szodoray Peter, Zeher Margit
Abstract excerpt
Autoimmune diseases are a family of chronic systemic inflammatory disorders, characterized by the dysregulation of the immune system which finally results in the break of tolerance to self-antigen. Several studies suggest that Toll-like receptors (TLRs) play an essential role in the pathogenesis of autoimmune diseases. TLRs belong to the family of pattern recognition receptors (PRRs) that recognize a wide range...
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