Article
The role of toll-like receptors in chronic inflammation.
The international journal of biochemistry & cell biology - 1 Apr 2010
Drexler Stefan K, Foxwell Brian M
Abstract excerpt
The role of Toll-like receptors (TLRs) in innate immunity and their ability to recognise microbial products has been well characterised. TLRs are also able to recognise endogenous molecules which are released upon cell damage and necrosis and have been shown to be present in numerous autoimmune diseases. Therefore, the release of endogenous TLR ligands during inflammation and consequently the activation of TLR...
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