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Article

Genotyping of CYP2C19 polymorphisms and its clinical validation in the ethnic Arab population.

The Journal of pharmacy and pharmacology - 1 Jul 2015

Tayeb Hamsa T, Bakheet Dana H, Zaza Khaled, Wakil Salma M, Dzimiri Nduna

Abstract excerpt

OBJECTIVES: The drug-metabolizing enzymes and transporters (DMET) Plus microarray and x-Tag assays have recently been developed for genotyping individuals in personalized medicine. Furthermore, the cytochrome 450-2C19 (CYP2C19) is a key metabolic enzyme encoded by a polymorphic gene commonly associated with diminished metabolism and variable clinical responses to several drugs in an ethnicity-dependent fashion....

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Identifiers

PMID: 25684066
DOI: 10.1111/jphp.12391

Genes

MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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