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Animal Models for Understanding the Mechanisms of Beta Cell Death during Type 2 Diabetes Pathogenesis

20 Feb 2024

Abstract excerpt

Type 2 diabetes (T2D) has become a worldwide epidemic, primarily driven by obesity from overnutrition and sedentariness. Recent results reveal there is heterogeneity in both pathology and treatment responses in T2D patients. Therefore, a variety of T2D animal models are necessary to obtain a mechanistic understanding of distinct disease processes. T2D results from insufficient insulin, either due to beta cell...

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PMID: 38540087
DOI: 10.3390/biomedicines12030473

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