Article
Plasma thiols levels in Alzheimer's disease mice under diet-induced hyperhomocysteinemia: effect of S-adenosylmethionine and superoxide-dismutase supplementation.
Journal of Alzheimer's disease : JAD - 1 Jan 2015
Persichilli Silvia, Gervasoni Jacopo, Di Napoli Alessandra, Fuso Andrea, Nicolia Vincenzina, Giardina Bruno, Scarpa Sigfrido, Desiderio Claudia, Cavallaro Rosaria A
Abstract excerpt
Widely confirmed reports were published on association between hyperhomocysteinemia, B vitamin deficiency, oxidative stress, and amyloid-β in Alzheimer's disease (AD). Homocysteine, cysteine, cysteinylglycine and glutathione are metabolically interrelated thiols that may be potential indicators of health status and disease risk; they all participate in the metabolic pathway of homocysteine. Previous data obtained...
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