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Article

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels.

Neurobiology of disease - 1 Jun 2006

Pacheco-Quinto Javier, Rodriguez de Turco Elena B, DeRosa Steven, Howard Altovise, Cruz-Sanchez Felix, Sambamurti Kumar, Refolo Lorenzo, Petanceska Suzana, Pappolla Miguel A

Abstract excerpt

Recent epidemiological and clinical data suggest that elevated serum homocysteine levels may increase the risk of developing Alzheimer's disease (AD), but the underlying mechanisms are unknown. We tested the hypothesis that high serum homocysteine concentration may increase amyloid beta-peptide (...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16516482
DOI: 10.1016/j.nbd.2006.01.005

Genes

APP
CBS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16516482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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