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Article

Helicase‐Primase as a Target of New Therapies for Herpes Simplex Virus Infections

18 Nov 2014

Abstract excerpt

The seminal discovery of acyclovir 40 years ago heralded the modern era of truly selective antiviral therapies and this drug remains the therapy of choice for herpes simplex virus infections. Yet by modern standards, its antiviral activity is modest and new drugs against novel molecular targets such as the helicase-primase have the potential to improve clinical outcome, particularly in high-risk patients. A brief...

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PMID: 25670384
DOI: 10.1002/cpt.3

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