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Article

The DNA helicase–primase complex as a target for herpes viral infection

12 Aug 2013

Abstract excerpt

INTRODUCTION: The Herpesviridae are responsible for debilitating acute and chronic infections, and some members of this family are associated with human cancers. Conventional anti-herpesviral therapy targets the viral DNA polymerase and has been extremely successful; however, the emergence of drug-resistant virus strains, especially in neonates and immunocompromised patients, underscores the need for continued...

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Share to Cytomegalovirus and herpesvirus research
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PMID: 23930666
DOI: 10.1517/14728222.2013.827663

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