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Article

Helicases as antiviral drug targets

1 Jan 2003

Abstract excerpt

Helicases catalytically unwind duplex DNA or RNA using energy derived from the hydrolysis of nucleoside triphosphates and are attractive drug targets because they are required for viral replication. This review discusses methods for helicase identification, classification and analysis, and presents an overview of helicases that are necessary for the replication of human pathogenic viruses. Newly developed methods...

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Identifiers

PMID: 12973446
DOI: 10.1358/dnp.2003.16.6.829307

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Source receipt: pubmed, retrieved 7 Sept 2026.

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