Article
Mechanical forces modulate alveolar epithelial phenotypic expression.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology - 1 May 2001
Dobbs L G, Gutierrez J A
Abstract excerpt
Physical forces play an important role in modulating lung development, growth, compliance, differentiation and metabolism. Both tonic distension and phasic changes in volume occur during development and after birth. Morphometric studies have shown that alveolar epithelial cells are distended during lung expansion from functional residual capacity. In both in vivo and in vitro model systems, mechanical distension...
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