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Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).

Diabetes care - 1 May 2015

Steck Andrea K, Vehik Kendra, Bonifacio Ezio, Lernmark Ake, Ziegler Anette-G, Hagopian William A, She JinXiong, Simell Olli, Akolkar Beena, Krischer Jeffrey, Schatz Desmond, Rewers Marian J

Abstract excerpt

OBJECTIVE: While it is known that there is progression to diabetes in <10 years in 70% of children with two or more islet autoantibodies, predictors of the progression to diabetes are only partially defined. RESEARCH DESIGN AND METHODS: The Environmental Determinants of Diabetes in the Young (TEDDY) study has observed 8,503 children who were at increased genetic risk for autoimmune diabetes. Insulin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25665818
DOI: 10.2337/dc14-2426
PMCID: PMC4407751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).PMID 25665818Read ↗

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study.Semantic proximity Read ↗

Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study.Semantic proximity Read ↗

Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study.Semantic proximity Read ↗

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.Semantic proximity Read ↗

Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress ReportSemantic proximity Read ↗

Late-onset islet autoimmunity in childhood: the Diabetes Autoimmunity Study in the Young (DAISY).Semantic proximity Read ↗

The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report.Semantic proximity Read ↗

Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children.Semantic proximity Read ↗

Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study.Semantic proximity Read ↗

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children.Semantic proximity Read ↗

Family history of type 2 diabetes delays development of type 1 diabetes in TEDDY children with islet autoimmunity.Semantic proximity Read ↗

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.Semantic proximity Read ↗

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