Article
HLA-G expressing DC-10 and CD4+ T cells accumulate in human decidua during pregnancy
11 Dec 2012
Abstract excerpt
Multiple mechanisms underlie the surprising willingness of mothers to tolerate the semi-allogeneic fetal tissues during pregnancy. Chief among these is the expression of the HLA-G molecules that has been largely demonstrated to be responsible for reprogramming the local maternal immune response towards tolerance. We recently identified a subset of tolerogenic dendritic cells, DC-10 that secrete high amounts of...
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